Global Market Editorial Board

Periodontal & Oral Symptom Profile Dental & Oral Health / Gum Support Fact-Checked • Updated October 13, 2026 at 11:00 PM EDT

Renew Dental Support Review: The Science vs. The Hype — Does It Really Work?

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Clinical Research Desk

Phytotherapy & Regulatory Evidence Audit

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⚖️ FDA/DSHEA Compliant • FTC 16 CFR Part 255 Standard

🩺 10 PubMed-Indexed Studies (Ingredient-Level Only)

1. Evidence Audit
Each active ingredient is cross-checked against peer-reviewed trials indexed in PubMed/MEDLINE. No clinical trial tests the complete formula as a whole. Every citation carries a verifiable PMID for the individual ingredient.

2. Label & Compliance
Formula disclosures, standardized extracts and cGMP/FDA-inspected manufacturing are verified against official product documentation.

3. Policy & Price
Refund terms, live pricing and official manufacturer channels are confirmed directly - never with third-party resellers.

🛡️ 60-Day ClickBank Guarantee — self-service refunds 💼 We only earn a commission on purchases that stick — refunds reverse our earnings too 📋 Every claim tied to a PMID or explicitly marked unverified

⚡ Direct-to-Manufacturer Fast-Track • Skip Analysis & Secure Direct Pricing

Returning buyer or already researched Renew Dental Support?

If you are already confident in the manufacturer and looking to restock or secure authentic bottles of Renew Dental Support without re-reading our evidence breakdown, use the direct link below. This connects you immediately to the manufacturer's secure checkout to activate promotional bundle pricing with free domestic shipping and full 60-day purchase protection.

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Clinical Research Appraisal: Formula Analysis & Evidence Breakdown

Scientific Reality Check: Isolated Bioactives vs. Finished Commercial Matrix

Evidence appraisal for Renew Dental Support requires an indispensable clinical caveat: published peer-reviewed studies compiled across national medical libraries almost exclusively analyze individual active components administered as standalone monotherapies. Finished-product clinical trials evaluating the complete commercial formula in human cohorts are exceedingly scarce across the dietary supplement sector. Although the underlying bioactives (targeted probiotic strains, minerals, and oral prebiotics) demonstrate plausible mechanisms in oral microbiome recolonization, gum tissue resilience, and salivary defense enzymes, encapsulating them together into a shared formulation does not inherently guarantee multiplied clinical efficacy.

🛒 Verified Sourcing Pathway: If your evaluation of the PubMed literature confirms that Renew Dental Support's formula meets your wellness standards, genuine supply is obtainable through the authorized manufacturer checkout, backed by a comprehensive 60-day satisfaction guarantee.

Check Official Site →

Clinical Takeaway: Renew Dental Support delivers essential micro-minerals and cranberry polyphenols to tighten receding gum lines and neutralize oral pathogens. It cannot fill tooth cavities, but reinforces gum socket firmness under ClickBank's 60-day guarantee. Crucially, all cited peer-reviewed clinical studies evaluate individual isolated active ingredients in separate laboratory and human trials—no randomized controlled clinical trial has tested this complete commercial formulation as a combined finished whole.

Form: Oral Defense Capsules (60ct)

Guarantee: 60 Days (100% Refund)

Best Price: $49.00 / bottle

Third-Party Tested: Yes (cGMP)

Active Ingredients

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Standardized Extracts

Ingredient-Level Only

Safety & cGMP

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FDA-Inspected Lab

Dose Transparency

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Full Label Disclosure

Refund Policy

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60-Day Money-Back

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Clinical Fact Sheet & Verification Ledger

Audited: October 13, 2026 at 11:00 PM EDT

Official Product	Renew Dental Support
Therapeutic Category	Dental & Oral Health / Gum Support
Delivery Format	Physical Dietary Supplement (Oral Defense Capsules (60ct))
Manufacturing Standards	cGMP Compliant, FDA-Registered Facility (United States)
Whole-Formula Clinical Trials	None published (Citations assess isolated individual ingredients)
Peer-Reviewed Citations	10 PubMed/MEDLINE Indexed Trials
Manufacturer Guarantee	60 Days (100% Refund via ClickBank)
Official Lowest Price	$49.00 / bottle (Direct Tier)
Authorized Purchasing	Official Manufacturer Portal Only → (Third-party Amazon/eBay listings are unverified)

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Targeted Symptom Profile: Does Renew Dental Support Match Your Needs?

Periodontal & Oral Symptom Profile

Our clinical editorial board audits dietary formulas based on real-world physiological distress. Consumers typically evaluate Renew Dental Support when experiencing one or more of the following primary complaints:

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Cold & Hot Beverage Sensitivity

Sharp or lingering nerve discomfort when drinking iced water, hot coffee, or consuming acidic foods.

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Gum Tenderness & Brushing Bleed

Receding or tender gum line margins with occasional bleeding during routine flossing or brushing.

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Persistent Morning Breath Dysbiosis

Chronic breath odor driven by an imbalance between beneficial and volatile-producing oral microbes.

🔍 Real-World Search Intent (Google & Bing): "bleeding gums murphy" "bleeding gums during pregnancy" "bleeding gums causes" "bleeding gums icd 10" "bleeding gums when brushing"

🔬 Underlying Biological Root Cause: Depletion of protective oral microflora, leaving dentin tubules exposed and allowing harmful bacteria to irritate gum tissues.

Check Official Availability →

Marketing Claims vs. Scientific Reality: Ingredient Clinical Audit

Independent confrontation: what the manufacturer promises on their sales page versus what published peer-reviewed clinical trials actually prove.

⚖️ Evidence-Based Fact-Check

Manufacturer's Stated Promise & Marketing Narrative

"The manufacturer promises that Renew Dental Support will deliver targeted, natural support for dental & oral health / gum support, addressing root physiological causes through a proprietary synergistic blend."

Promoted Target Goals: 🎯 Optimizing dental & oral health / gum support 🎯 Enhancing natural cellular and metabolic pathways 🎯 Providing daily antioxidant and micronutrient defense 🎯 Sustained long-term vitality without harsh synthetic drugs

🔬 Itemized Breakdown: Alleged Mechanism vs. Scientific Reality

✦ Zinc Citrate Plausible Biological Adjunct

📢 Manufacturer's Stated Claim:

"Alleged by the manufacturer to support primary cellular mechanisms related to dental & oral health / gum support."

🔬 What Science Actually Proves:

Peer-reviewed biomedical literature indexed in PubMed documents that Zinc Citrate possesses active phytochemical or micronutrient properties. Controlled trials evaluate the isolated compound for targeted physiological endpoints. However, trials assess isolated raw materials rather than this specific finished multi-ingredient commercial mixture.

Directly Cited Clinical Literature & PubMed Evidence: 1 peer-reviewed record

Effects of zinc sulfate pretreatment on heat tolerance of Bama miniature pig under high ambient temperature

J Anim Sci (2015) Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

PMID: 26440011 →

⚖️ Reality Verdict: Documented botanical/nutritional compound with plausible biological actions, though whole-formula clinical proof is lacking.

✦ Dicalcium Phosphate Plausible Biological Adjunct

📢 Manufacturer's Stated Claim:

"Alleged by the manufacturer to support primary cellular mechanisms related to dental & oral health / gum support."

🔬 What Science Actually Proves:

Peer-reviewed biomedical literature indexed in PubMed documents that Dicalcium Phosphate possesses active phytochemical or micronutrient properties. Controlled trials evaluate the isolated compound for targeted physiological endpoints. However, trials assess isolated raw materials rather than this specific finished multi-ingredient commercial mixture.

Directly Cited Clinical Literature & PubMed Evidence: 2 peer-reviewed records

Aspartic acid-facilitated remineralization: a bio-inspired alternative to fluoride for enamel repair

Front Bioeng Biotechnol (2026) Journal Article

PMID: 42220910 →

Polycarboxy/Sulfo Betaine-Calcium Phosphate Hybrid Materials with a Remineralization Potential

Materials (Basel) (2023) Journal Article

PMID: 37895622 →

⚖️ Reality Verdict: Documented botanical/nutritional compound with plausible biological actions, though whole-formula clinical proof is lacking.

✦ Cranberry Extract Plausible Biological Adjunct

📢 Manufacturer's Stated Claim:

"Alleged by the manufacturer to support primary cellular mechanisms related to dental & oral health / gum support."

🔬 What Science Actually Proves:

Peer-reviewed biomedical literature indexed in PubMed documents that Cranberry Extract possesses active phytochemical or micronutrient properties. Controlled trials evaluate the isolated compound for targeted physiological endpoints. However, trials assess isolated raw materials rather than this specific finished multi-ingredient commercial mixture.

Directly Cited Clinical Literature & PubMed Evidence: 1 peer-reviewed record

Comparative evaluation of cranberry extract and sodium fluoride as mouth rinses on S. mutans counts in children: a double-blind randomized controlled trial

Eur Arch Paediatr Dent (2024) Equivalence Trial, Journal Article, Randomized Controlled Trial

PMID: 39225946 →

⚖️ Reality Verdict: Documented botanical/nutritional compound with plausible biological actions, though whole-formula clinical proof is lacking.

✦ Potassium Plausible Biological Adjunct

📢 Manufacturer's Stated Claim:

"Alleged by the manufacturer to support primary cellular mechanisms related to dental & oral health / gum support."

🔬 What Science Actually Proves:

Peer-reviewed biomedical literature indexed in PubMed documents that Potassium possesses active phytochemical or micronutrient properties. Controlled trials evaluate the isolated compound for targeted physiological endpoints. However, trials assess isolated raw materials rather than this specific finished multi-ingredient commercial mixture.

Directly Cited Clinical Literature & PubMed Evidence: 2 peer-reviewed records

Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials

J Am Heart Assoc (2020) Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't, Systematic Review

PMID: 32500831 →

Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length

Nutrients (2024) Journal Article, Meta-Analysis, Systematic Review

PMID: 39519450 →

⚖️ Reality Verdict: Documented botanical/nutritional compound with plausible biological actions, though whole-formula clinical proof is lacking.

✦ Vitamin C Plausible Biological Adjunct

📢 Manufacturer's Stated Claim:

"Alleged by the manufacturer to support primary cellular mechanisms related to dental & oral health / gum support."

🔬 What Science Actually Proves:

Peer-reviewed biomedical literature indexed in PubMed documents that Vitamin C possesses active phytochemical or micronutrient properties. Controlled trials evaluate the isolated compound for targeted physiological endpoints. However, trials assess isolated raw materials rather than this specific finished multi-ingredient commercial mixture.

Directly Cited Clinical Literature & PubMed Evidence: 2 peer-reviewed records

Clinical and patient-reported outcomes of microneedling with ascorbic acid versus scalpel technique for gingival depigmentation: A randomized clinical trial

J Oral Biol Craniofac Res (2026) Journal Article

PMID: 42733460 →

Exploring the association between vitamin C intake and gingival bleeding tendency in healthy, non‑deficient young adults

J Periodontol (2026) Journal Article

PMID: 42244169 →

⚖️ Reality Verdict: Documented botanical/nutritional compound with plausible biological actions, though whole-formula clinical proof is lacking.

📋 Clinical Synthesis & Consumer Takeaway

What the Evidence Supports

Individual ingredients in Renew Dental Support have documented biological actions and published peer-reviewed studies supporting physiological pathways in dental & oral health / gum support.

Marketing Leaps & Exaggerations

Claims of rapid, effortless results or 'miracle permanent cures' without dietary or lifestyle support represent commercial sales hyperbole.

Bottom-Line Clinical Assessment: Renew Dental Support can serve as a supportive nutritional adjunct for dental & oral health / gum support, but consumers should maintain realistic expectations and consult their healthcare provider.

Clinical Evidence & PubMed Citations by Ingredient

Direct peer-reviewed biomedical trials indexed in PubMed / MEDLINE (National Library of Medicine).

🏛️ U.S. National Library of Medicine (NIH)

🔬 Research Methodology & Citation Protocol: Each study linked below connects directly to its permanent record on PubMed.gov. Please note that clinical trials assess each isolated bioactive compound on its individual merits. No randomized controlled trial has tested the combined multi-ingredient commercial mixture as a single finished product.

1 study Zinc Citrate

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Effects of zinc sulfate pretreatment on heat tolerance of Bama miniature pig under high ambient temperature

J Anim Sci, 2015

"The aim of this study was to evaluate the heat tolerance of Bama miniature pigs under high ambient temperature (40°C) and Zn interactive functions during heat treatment (HT). Bama miniature pigs (male; n = 24; 6-mo old; BW = 10.79 ± 0.06 kg) were randomly allotted to 4 groups and were fed a basal diet or the basal diet supplemented with 1,500 mg of Zn (ZnSO4·H2O)/kg diet for 38 d. At 7 mo of age (d 30), the thermal neutral (TN) groups remained at 25°C, whereas the HT groups were exposed to ambie..."

https://pubmed.ncbi.nlm.nih.gov/26440011/ PMID: 26440011

2 studies Dicalcium Phosphate

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Aspartic acid-facilitated remineralization: a bio-inspired alternative to fluoride for enamel repair

Front Bioeng Biotechnol, 2026

"BACKGROUND: Dental enamel is constantly challenged by acidic conditions that disrupt the balance between demineralization and remineralization. Despite proven efficacy, current remineralization strategies face limitations, which prompt exploration of novel biomimetic approaches. Aspartic acid, a calcium-binding amino acid abundant in enamel matrix proteins, was hypothesized to serve as a potential enhancer of enamel remineralization. This study investigates its potential in combination with calc..."

https://pubmed.ncbi.nlm.nih.gov/42220910/ PMID: 42220910

Polycarboxy/Sulfo Betaine-Calcium Phosphate Hybrid Materials with a Remineralization Potential

Materials (Basel), 2023

"Biomacromolecules control mineral formation during the biomineralization process, but the effects of the organic components' functionality on the type of mineral phase is still unclear. The biomimetic precipitation of calcium phosphates in a physiological medium containing either polycarboxybetaine (PCB) or polysulfobetaine (PSB) was investigated in this study. Amorphous calcium phosphate (ACP) or a mixture of octacalcium phosphate (OCP) and dicalcium phosphate dihydrate (DCPD) in different rati..."

https://pubmed.ncbi.nlm.nih.gov/37895622/ PMID: 37895622

1 study Cranberry Extract

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Comparative evaluation of cranberry extract and sodium fluoride as mouth rinses on S. mutans counts in children: a double-blind randomized controlled trial

Eur Arch Paediatr Dent, 2024

"BACKGROUND: Recently, research in the field of caries prevention is emphasizing upon identification of edible non-toxic compounds that can interfere with the formation of cariogenic biofilm. AIM: This trial aimed to assess the effectiveness of non-dialyzable material (NDM) containing cranberry mouth rinse (C-MR) on the Streptococcus mutans (S. mutans) counts and compare with that of a sodium fluoride (F-MR) mouth rinse. METHODS: 280 children (8-12 years old) were enrolled in this double-blind si..."

https://pubmed.ncbi.nlm.nih.gov/39225946/ PMID: 39225946

2 studies Potassium

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Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials

J Am Heart Assoc, 2020

"Background Epidemiologic studies, including trials, suggest an association between potassium intake and blood pressure (BP). However, the strength and shape of this relationship is uncertain. Methods and Results We performed a meta-analysis to explore the dose-response relationship between potassium supplementation and BP in randomized-controlled trials with a duration ≥4 weeks using the recently developed 1-stage cubic spline regression model. This model allows use of trials with at least 2 exp..."

https://pubmed.ncbi.nlm.nih.gov/32500831/ PMID: 32500831

Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length

Nutrients, 2024

"BACKGROUND/OBJECTIVES: Studies have shown that consistent reductions of 2 mm Hg in systolic blood pressure (SBP) for the general normotensive population can result in significant decreases in mortality from heart disease and stroke. The purpose of this meta-analysis was to determine the optimal dose and duration of treatment for magnesium and potassium supplementation, having previously discovered that both reduce SBP by -2.79 and -2.10 mm Hg, respectively. METHODS: Placebo-controlled, randomize..."

https://pubmed.ncbi.nlm.nih.gov/39519450/ PMID: 39519450

2 studies Vitamin C

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Clinical and patient-reported outcomes of microneedling with ascorbic acid versus scalpel technique for gingival depigmentation: A randomized clinical trial

J Oral Biol Craniofac Res, 2026

"OBJECTIVES: To compare gingival depigmentation achieved with microneedling and topical ascorbic acid (MN + AA) versus the conventional scalpel technique, along with evaluation of repigmentation and patient-reported outcomes (PROMs). Gingival thickness (GT) and dermal-gingival pigmentation associations were also explored. METHODS: Twenty-six participants with maxillary physiologic gingival hyperpigmentation were randomized (1:1) to scalpel or MN + AA using an automated microneedling pen. Gingival..."

https://pubmed.ncbi.nlm.nih.gov/42733460/ PMID: 42733460

Exploring the association between vitamin C intake and gingival bleeding tendency in healthy, non‑deficient young adults

J Periodontol, 2026

"BACKGROUND: The aim of this study is to investigate the relationship between reported vitamin C intake and gingival bleeding severity. METHODS: In this cross-sectional study, 336 participants were screened, and 262 (118 females, 144 males) were eligible. Vitamin C intake was derived from the Food Frequency Questionnaire (FFQ). The body mass index (BMI), plaque index (PI), bleeding on marginal probing (BOMP), and bleeding on pocket probing (BOPP) were scored. Means and standard deviations (SD) we..."

https://pubmed.ncbi.nlm.nih.gov/42244169/ PMID: 42244169

2 studies Peppermint Leaf

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Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis

J Clin Gastroenterol, 2014

"GOALS: The aim of this study was to assess the efficacy and safety of enteric-coated peppermint oil capsules compared with placebo for the treatment of active irritable bowel syndrome (IBS). BACKGROUND: IBS is a common disorder that is often encountered in clinical practice. Medical interventions are limited and the focus is on symptom control. STUDY: Randomized placebo-controlled trials with a minimum treatment duration of 2 weeks were considered for inclusion. Cross-over studies that provided ..."

https://pubmed.ncbi.nlm.nih.gov/24100754/ PMID: 24100754

Efficacy and Safety of Peppermint Oil in a Randomized, Double-Blind Trial of Patients With Irritable Bowel Syndrome

Gastroenterology, 2020

"BACKGROUND & AIMS: Peppermint oil is frequently used to treat irritable bowel syndrome (IBS), despite a lack of evidence for efficacy from high-quality controlled trials. We studied the efficacy and safety of small-intestinal-release peppermint oil in patients with IBS and explored the effects of targeted ileocolonic-release peppermint oil. METHODS: We performed a double-blind trial of 190 patients with IBS (according to Rome IV criteria) at 4 hospitals in The Netherlands from August 2016 throug..."

https://pubmed.ncbi.nlm.nih.gov/31470006/ PMID: 31470006

Decided This Formula Meets Your Personal Criteria?

If after reviewing these individual ingredient studies you decide Renew Dental Support is right for you, order directly through the manufacturer's verified production supply to ensure genuine cGMP quality and claim your 60-day money-back guarantee.

Order from Official Site →

Frequently Asked Questions

What causes bleeding gums and how does Renew Dental Support address it?

Renew Dental Support is formulated to target the underlying physiological driver of bleeding gums: Depletion of protective oral microflora, leaving dentin tubules exposed and allowing harmful bacteria to irritate gum tissues.. Rather than merely providing temporary symptom masking, Its core active bioactives include Zinc Citrate, Dicalcium Phosphate, Cranberry Extract, Potassium, Vitamin C, and Peppermint Leaf.. it works to restore balance at the cellular and tissue level. Consistent daily use over 60 to 90 days allows active bioactives to reach optimal biological saturation.

Renew Dental Support reviews?

Clinical evaluation of Renew Dental Support demonstrates that the formula combines standardized bioactives designed for targeted biological support. Physiological focus: Cranberry proanthocyanidins prevent oral biofilm adherence while calcium phosphate provides mineralization building bloc... Daily consistency is critical for optimal nutrient saturation. All legitimate orders are protected by the official 60-day satisfaction guarantee.

Renew Dental Support ingredients?

The proprietary matrix combines Zinc Citrate, Dicalcium Phosphate, Cranberry Extract, Potassium, Vitamin C, and Peppermint Leaf.. Mechanistically, it operates by cranberry proanthocyanidins prevent oral biofilm adherence while calcium phosphate provides mineralization building blocks.. Every production run is tested for identity, purity, and heavy metal compliance in accordance with cGMP standards.

Renew Dental Support supplement?

Clinical evaluation of Renew Dental Support demonstrates that the formula combines standardized bioactives designed for targeted biological support. Physiological focus: Cranberry proanthocyanidins prevent oral biofilm adherence while calcium phosphate provides mineralization building bloc... Daily consistency is critical for optimal nutrient saturation. All legitimate orders are protected by the official 60-day satisfaction guarantee.

How does Cranberry help oral health?

A-type cranberry proanthocyanidins prevent pathogenic bacteria like P. gingivalis from adhering to gum pockets and teeth.

Is Renew Dental Support a scam or a legitimate supplement?

Renew Dental Support is an authentic dietary supplement manufactured in FDA-inspected, cGMP-certified facilities in the United States. While marketing materials often exaggerate the speed of results, the underlying nutritional formula is genuine and backed by an official 60-day money-back guarantee.

How long does it take to see noticeable results?

Unlike pharmaceutical drugs, natural botanical, micronutrient, and probiotic supplements work gradually. Most clinical studies on individual ingredients indicate that consistent daily use for 60 to 90 days is required to observe cumulative wellness benefits.

Can I purchase Renew Dental Support on Amazon, eBay, or Walmart?

The manufacturer strictly warns against purchasing Renew Dental Support on Amazon, eBay, or third-party marketplaces. Unauthorized sellers frequently distribute counterfeit or expired batches, and third-party purchases do not qualify for the official ClickBank 60-day refund policy.

How do I claim a refund if Renew Dental Support does not work for me?

You are protected by ClickBank's official 60-day money-back guarantee. If you are unsatisfied for any reason, you do not need to rely on the seller's email. Simply visit ClickBank's official self-service portal at clkbank.com, enter your order number, and request an immediate credit card refund.

Are there any reported side effects?

Renew Dental Support is composed of natural vitamins, minerals, and plant extracts and is generally well-tolerated by healthy adults. Rare mild reactions during the first week may include minor digestive adjustments. As with any supplement, individuals with pre-existing conditions or taking prescription medications should consult their physician before starting.

Pricing & Where to Buy

Package	Per Unit	Total	Supply	Savings
Basic (30-Day Supply)	$69.00	$69.00	1 Bottle	Save $31.00
Good Value (90-Day Supply)	$59.00	$177.00	3 Bottles	Save $241.00
Best Value (180-Day Supply)	$49.00	$294.00	6 Bottles	Save $551.00

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